Stem cells and Platelet-rich plasma for facial rejuvenation
1 What is platelet rich plasma PRP?
2 How does PRP work?
3. Which are the benefits of platelet rich plasma?
4 What is facial stem cell therapy?
5 How do stem cells work?
6 How is the Stem cells and PRP application like during facelift?
7 Who are these treatments indicated for?
8 Are stem cells and Platelet rich plasma indicated for me?
Platelet-rich plasma for facial rejuvenation
1. What is platelet rich plasma or PRP?
Platelet-rich plasma is concentrated plasma, prepared by centrifugation to separate the red blood cells. To obtain it, 15 cc of blood is removed from the arm.
The PRP of platelet-rich plasma is widely applied in several surgical specialties for its ability to stimulate wound healing and minimize bleeding during surgery.
2. How does PRP work?
The activation of platelets through coagulation triggers the secretion of several growth factors, which produce mitogenic effects (cell multiplication) in various cell types.
Platelet Rich Plasma (PRP) induces the synthesis of components of the collagen matrix and other chemical mediators, which in turn stimulate the activation of the fibroblasts that produce collagen and elastin, and consequently produces the rejuvenation of the skin.
3. Which are the benefits of platelet rich plasma?
New reports indicate that rejuvenating effects appear after intradermal injection of growth factor: improved skin softness, gradual improvement of turgor, improved thickness of atrophied skin, and greatly improved viscoelasticity which reveals the biomechanical properties of the treated aged skin improvement.
Some characteristics of Platelet rich plasma (PRP) are:
- PRP is autologous tissue (from the same patient). It does not cause immunologic reaction
- PRP helps with healing
- PRP reduces postoperative swelling, hematoma and seroma
- PRP secretes various growth factors with roles in skin regeneration.
Stem cells for facial rejuvenation
4. What is stem cell therapy for face?
Stem cells and Platelet rich plasma promote tissue remodeling in aged skin and is used as an adjuvant treatment to lipofilling and lasers for skin rejuvenation. Stem cell therapy could be used for face, neck, and hands.
5. How do stem cells work?
Adipose Derived Stem cells (ADSCs) produce many useful growth factors, increase collagen production and reverse skin aging.
Autologous mesenchymal stem cells are isolated from adipose tissue for treatment of facial wrinkles, frown lines, nasolabial folds, and crow’s feet.
6. How is the Stem cells and PRP application like during facelift?
Abdominal fat and peripheral blood are harvested the day of surgery to isolate ADSCs and autologous plasma in a single procedure. Liposuction can be performed under local anesthesia to obtain a small amount of fat with this purpose.
The stem cells are isolated and then injected combined with PRP to improve healing process, and reverse aging. ADSCs is combined with fat when necessary, to add volume in certain areas like cheeks, lips, and lower eyelid.
The stem cells when combined with fat is capable to fill deep creases, nasolabial folds, glabelar line, with progressive improvement of skin tone and decreasing lines of expression.
During facelift the Stem Cells are injected in different layers to improve the healing process and to improve the quality of the soft tissues in the face; thus intend to improve long term results.
7. Who are these treatments indicated for?
These procedures can be useful in younger patients to treat initial signs of aging and are specially indicated in aged patients to regenerate tissue improving the quality of the skin and soft tissues.
Adipose-derived stem cells (ADSCs) and their secretory factors stimulate collagen synthesis and migration of fibroblasts during the wound healing process causing a biological rejuvenation.
When used in conjunction with a facelift procedure the results are potentiated because they produce a structural and biological improvement of the face.
After surgery a diode laser treatment is applied in a few sessions to induce new collagen synthesis via activation of dermal fibroblasts and growth factors.
Adipose-derived stem cells and their secretory factors is a promising easy-to-perform technique in face and neck rejuvenation. It can be performed alone, for instance, in patients that don’t want to undergo surgery; on these patients the results will vary according to the patient condition.
Platelet Rich Plasma (PRP) and Adipose Stem Cells (ASCs) are also used in conjunction with the following surgical procedures:
Buttock augmentation by fat grafting
Breast augmentation by fat grafting
Platelet-rich plasma also can be combined with:
- Juvederm or hyaluronic acid
- Diode laser
- Peelings or Dermabrasion
8. Are stem cells and Platelet rich plasma indicated for me?
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